See notes on MDLQA-11583 failure:
Looks like some validation problems on step 14 + 15 (I did these both before saving the settings form). Basically, I don't see any error about python path, and it just 'silently' saves the new time splitting methods and reverts the predictions processor to php without any warning/info. I'll create an MDL to address this now.

To replicate (all branches version):
As admin:

1. Go to Admin > Security > HTTP security
2. Enter the value ** in the cURL blocked hosts list field and save
3. Confirm you see a validation warning
4. Now, check the 'Only http cookies' checkbox and save again
5. Notice that you don't see a warning about the ** value this time and that the other value (checkbox) has saved.
6. Now, change only the blocked hosts field and save
7. Notice the warning that should have occurred earlier.