With MySQL 8 and MariaDB 10.3.1/10.6.0 various parameters were removed:

• innodb_file_format[_check|_max]: Only file format is Barracuda, so the parameters have been removed.
• innodb_large_prefix: With the Barracuda format, the default is to have this parameter enabled, so it has been removed too.

This issue is about to look for all the uses of them in core and only try to report or use them when available.

Take a look to is_antelope_file_format_no_more_supported() because it already has some code detecting it.

This affects specifically to various admin/cli/mysql_**** scripts.

$ ag '(innodb_large_prefix|innodb_file_format)' -l

admin/cli/mysql_collation.php

admin/cli/mysql_compressed_rows.php

lang/en/admin.php

lib/dml/mysqli_native_moodle_database.php

lib/ddl/tests/ddl_test.php

lib/upgradelib.php